The nerve cells are those running diagonally down the middle of the pic. |
Other Key Things to Remember:
-The anatomical names of the nerve connective coverings are the same as muscle (epi-, peri-, and endoneurium), but the histological classifications are slightly different. Remember that the epineurium is the thickest covering that surrounds the entire nerve. Anything that is cutting through the middle of the nerve will be perineurium, and anything surrounding a single fiber/axon will be endoneurium.
-What stains nerve tissue??? (hint: Gold, _____, Bronze)
-Know what satellite cells are, where to find them (p. 46), and what they do.
-For the central nervous system, don't go off of the color of the tissue on the slides to determine what is white/grey matter because white matter can be the darker of the two... you think they would have figured that one out right??? :) Remember from your anatomy days that the brain is like an oreo (grey matter on the outside, white on the inside) and your spinal cord is like a hotdog (white on the outside and grey on the inside).
-Make sure you can ID the dorsal and ventral sides of the spinal cord. The easiest way for me to do that is to remember the pneumonic "Heading to the back dor (like door, stands for dorsal)." Let me explain... the dorsal horn is in the back, and it touches the edge of the spinal cord while the ventral horn does not. It looks like the DORsal horn is heading to the back door. Also, the dorsal horn is usually narrower. Whatever works for you!
See the dorsal horn heading to the back door??? |
-For the cerebellum, know the layers and how to ID them on a slide or on a U-Find. They're pretty logical though - white matter on the inside (remember... OREO!!), then comes the granular layer which looks.... very granular :) (always does...), and the outermost layer is the molecular layer (think: molecules are smaller than granules... can't really see molecules). In between the molecular and granular layers is the purkinje cell layer (looks like a row of nerve cells separating the two layers). Here are some pics for your viewing pleasure...
This picture should look familiar to all of those who are in physiology. Aren't those purkinje cells cool?!?! Which layer is more granular looking? |
If you're having a hard time orienting yourself, look for the sulci (grooves of the brain). |
-Ependymal cells - where are they present??? (choroid plexus and central canal). Remember that they change histologically over time. I like the remember it this way: as you get old, you get short and bald (ciliated simple columnar --> sparsely ciliated simple cuboidal -->simple squamous).
-Auerbach's and Meissner's plexi both help regulating peristalsis. Auerbach's is found between the inner circular and outer longitudinal layers (think Auerbach sounds Austrian, kinda like Arnold Schwarzenegger, who has lots of muscles . . . so Auerbach's is gunna be between all those muscles). Zoom in and look for cells that fit the look of the ones at the beginning of this blog post. I prefer to look in the jejunum for these plexi, just because there aren't really any other structures there to confuse them with (no Brunner's or Peyer's patches). The Meissner's plexus is found at the very basal edge of the submucosa right before you get to the inner circular muscle layer (think Meissner Mucosa). Once again, zoom in and scan around until you find something that fits the profile of a nerve cell.
Here's a little game of "Where's Waldo" for you. These pictures were both taken of that slide.
Meissner's (Base of sub-mucosa) |
Auerbach's (lighter clustered structures toward the left-middle) - notice the smooth muscle on either sides?? |
Other Random Pics:
Meissner's |
Auerbach's (notice the muscle layers on either side) |
Notice how the ganglionic cell layer is thick here? (see E) However, the nuclei aren't as tightly packed, are larger, and have colored cytoplasm - fairly common characteristics for this layer |
-Make sure you know what neurons are unipolar, bipolar, etc. Some people like to remember it using the following: one tongue --> unipolar neuron, two ears --> modified bipolar neuron, two nostrils-->bipolar neuron, two retinas --> bipolar neuron.
Good luck on the quiz!! As always, feel free to let us know if you have any questions.
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